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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5236f111a999b8bd7241c40396b0a6a0a83000147b5388572f157895c1f63c' 
  AND token = 'cSz+NHgQHLvur9St8zFJKZy3s601YNbGJLOPqA0zI78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}