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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee6116067ebc764d3ef62d2d88b381c01da8e1208e6a96fb65c28d3e16f87a14' 
  AND token = '80Tb6mGAg+8QzqL0soOvmJcHZ1C7RPvJOiwW7Eag4W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}