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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437ba29e7150b1bc27be6a3b4ec771eabc5f844298da8d49035d30122999bfd3' 
  AND token = 'a6FC2QHGXizR6lEwdT5q/GHH4dbMud3Cd+3i5hSF1UE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}