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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8baeda522f071d7b2325066720d8c7a17d834e76bbeaca3f565fdb93ca945f' 
  AND token = '51XfuxvBg+rtRqp32PY5slNqwJ8Ay4ht+ONBgffcHdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}