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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45e8e4a2df18ae800b4a46ed069dbc480a905a4de899b852a18567d76ced70c9' 
  AND token = 'v1yiHUDCO1xf1nzpxXQpGgkbuyvfey1phaXMT1L9nnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}