SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c5c9e91c0d231609222e24802527bfdeeaf4c9dd022a3ce384b3543acbc797d' 
  AND token = 'oY3MamBi6cBLSXc4PcJZRpFROVdjqncsgdwXcJ+/hrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}