SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a2208e8b566d5de796cca5a48e7cfd3dc6d61356fb575d12c5d0b89abf172f7' 
  AND token = '8RM78b13jmmRMRAhgnL4mxWfAn3fHu7k/QskxbRuY88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}