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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d75d2c0c8401bd6fded2f4de1491a9f825dbde28bac99c98fd0b7ce83e5680' 
  AND token = 's2rvgICmBEBv8Y2Nn/h0V3ITJJcAWX0EV/btw+inuDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}