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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa23c0442a40944661e61ce2019b810e4a279e957cd8e07fdb14c77b5963901' 
  AND token = '33ZOrHg6Ar1WWr1w2IxCzt2gHP7BOK8xQbifsfjDhQ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}