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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5423ec0ddbbf7adeca3bd7ac642f2ca7482dc85d5a9ae169ae0ed7039ef8e3c' 
  AND token = '5jc8YatxyAHuEYfv8kk3TgGkyAk8w9AMQM4svu0tgdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}