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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce230f3bd99c7fdfb57cdf8cf1ce12a31cb99537a45250793a30a66f4f5003b' 
  AND token = '0ZoL6K15hGP9E5ffM7A5Ti7sxBf9MvtvsbvLWOpqHa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}