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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c45e59f268885a689ebaf89c01ac801ab291116901e45429f0a60b3c8d68334' 
  AND token = 'L33XQNBerSU9ZFcfkMPGAHlBI4WVJtfvlaDCP345HFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}