SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9fd07349a3dd3ff29e8da1acd8b867029852a38778fa8b594cf1da67f0fcbea' 
  AND token = 'Rc6WmUm+oyvWkM5RWF1VeolWr2wm3abN8bh+vaJbHxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}