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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4803b3db47632b04d94d3b30e73710c4adc4ae9f814d99c069999f47d333b580' 
  AND token = 'Ug+bcxwjZ+YsetOR1v3YQxRrTr4NFeHqIWdL2HbagZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}