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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b250bee5e432c57241f7b4691d15e9711c0492890b2d1dbfbd7329cdb0863fd' 
  AND token = 'G5Ebn2t5JcFLrhY1Ns5ChxlXrIdkW0i/4c920L4gz3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}