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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f6f15ef41bb03dfc7c220ddbdfbe6af82997b59f516a70678e4f15d10f99f3b' 
  AND token = 'ROkI7GpmJCoWT+M1CddLsjpjXORPtlXNaW+oxD5b5QY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}