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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f165a0955685fd27cdf4bbb13fbe9a706cc5adb7734d425a3b64f0fca180a6' 
  AND token = '17RCgXyUMT+TVq1zXXNzX8wNrVPvuT6iXWriA352LOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}