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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '76b55024db5abc3ba1c21efcbaa6be6e8278e83363d4d86cec39ac099a4af00f' 
  AND token = 'vI7Vvc8e+CyDOTgwDlow/ZaY70NgKNiiyzw69W1e0C4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}