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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '88e3aabc96272df2aec60852d7605e36f31f51009d6b66075e560cf6b677b765' 
  AND token = 'LYtgDV7aezhZ+37MtdqhY6pExVEBoYUAADmZr/tLPrg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}