SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb8cbaecd1420f53536ab8ba7e163fa4e717220317d1aeaa8d71269b0cea00a6' 
  AND token = 'IQ2O/nsh6qOxtgra2JrF61w95h7hYMyqXk/QptM+MbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}