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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c12df5e3d7777c039baab6327f8c7ab97b0ddfde60c0802485270439f8fbd1b' 
  AND token = 'GZj8nx4h1gjtqwfnnWJZPR2kMi4H7nYd7IqhPQSjlT4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}