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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43caba7cd79a4f3b8246d8656b7ecba8ed1067298b29b52b1cb7fb8da01c572b' 
  AND token = 'OEKR2lHX81N4wi+OWy34ev/ABfsfDx1rDH68sr+mn6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}