SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b122549e4ae7e75add3ce8447169cd370cd6a67a70f095f273859d3c5c76745a' 
  AND token = 'T+KrNBMVm7MbDQ3LYZtiuGPRyL1JHqRTccJ5i8nomwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}