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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7221cd923b5072b5dc354f7cdf7c2748601e448cc16ad16c953d2d8de730b922' 
  AND token = 'V1yJQixEbAd6hrPMd8PKI3nobmkAlR6v5l1NgGru2nI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}