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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd2d2957d050b0f865759a2aa566d11930772b3fe498466e1222c5b43c106915' 
  AND token = 'uqno+eyzJTpPBXW0xXh7n9/uZzLxfkZHz5G4ls5ocdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}