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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8226ca925ef2d7434b158e674ec870c8464a617d0cc4a89d22aae3959fbc7b8d' 
  AND token = 'kRpjELNzWa32C5GPEZCYVmVf8VAq/5lh9LFr3kUOkLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}