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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9008d68f12fd6d81101bfb206bc70eaf1820d977be6d576f4d67ee59821bdc45' 
  AND token = 'QJwo49qsP+3jz8sCnEoJMtEG8q0sPcsi5Jbdk4FtOQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}