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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15282f4dfe74212166c190e2c3fcf19a2826a8a3f3a5cba996f2c435edf0c1cb' 
  AND token = '1I1Saio4sqL9wuuk6dGqETu+EbgpRI1/6jFHBHjkEEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}