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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9b2f65428b364e5ba2653345591975ed37195cb2eebe2cd8ba85cdf893c3777' 
  AND token = 'e5KuRjZTW1M0hINgSdz3N4CIFLhXTpqhADCgP2WRXVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}