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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '56dbbd6702663d9363dbc2532805c620b231b18ae39fdd6a9600b4ff2f5db2e9' 
  AND token = 'e5uAdTOXoBKG8VKbXLYs9Uog5kbR14ZNPmNn2t6vbLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}