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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95a781a6fc1b3d01943473893748337fcc8c11b1c9da7719194bc6455d74977c' 
  AND token = 'B/xW94eoZcPwxPsMwk2nY2VhCxDqEo0+ivxDPfeC7oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}