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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1ed100a481b36250f4b6e2c3f79855aabceab782b8e37896d4c83368132efbf' 
  AND token = 'zy2h1SZdE2/O9l0UUsF3jF+WG0RtRNcOHkBpGKpdbd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}