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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '363f5889d850d75b158400241e656e62d56102bc340923d49c62d24a05a16184' 
  AND token = 'ds91t8QNnx0D4NHy+PuOpCthYcKjK5ByI5TJHwvo2eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}