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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00e9837f34667d645c2c0977d306c5d75c221af8dcd8d3eb89625d618924aa5' 
  AND token = 'RpJSZVvsqZIR7kdBTLwWWvDC9n1uAFoP4wXovk9NDG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}