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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ab711c45e54ef743bd57241a7c6fe64a3eeaa725d5568d8d741a31de58f04a' 
  AND token = 'IVan/3NAWxA6fz2kJt1v3wohlRTwcWk3a6uiBe/lDq0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}