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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '797277479e4ca97ca4e0277ace02a09f3059169dfe0e05c3faa0e605f73b0b91' 
  AND token = 'Vxidu0RKK1Wj+BkwTOJ9OgnMm0qEUAU1zuyyS6Df2e8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}