SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '629324e7848a5fe8e72be4fc7be489fde250178fbf3eb2f43fe102159d90f33c' 
  AND token = 'lv7B6YOR1oWoBdsfQRxjsrHc1X6pfLUXt1DfcjnXoV4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}