SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8678cf79e0ff33d9dc7e6a27ce93d54c927d74328d9edd22c1c1d8180dfd99c6' 
  AND token = 'jxZbbW/XP8FVueJIvBGW7ZImMOBjHN9eO4BKAVp+34o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}