SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cfcd0af32686b513e1271dfb718f5fee08c31173ab0cee1b4d2ec03a38469b' 
  AND token = 'Qb5WneKNdLlpJK76XeMzcB85W/3pP7SBx2VYu6NDAjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}