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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45b94474c76fab9f5baeabe260f3b3b794ec1d1727f6cf3713295cabf336f2a3' 
  AND token = 'Awj5EOygifRtcIPI+ojrwYVmKSbGrWu9Q+6CXrIlyXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}