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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0681178b1c092892af1286535b504d0fdc41b4de6a8a28496dda58f2dc4cd25b' 
  AND token = 'JMlknpC+CUd949nU8fUW4x9RaeY4+JhI1XMqXuNUdo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}