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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2887d963aac4c9b1399d69c7ade64fa29519ea5ae32f6005bdf1aab75d706af' 
  AND token = 'assQiBcfdMtKrVJ9rwsvE9tASZ4yzh8gIDsqZMQm7n8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}