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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b15b96d71ee20528dbaf74969ffb3d44c006f66e92a331892446d849a08b584' 
  AND token = 'TnUO8Ko9+WdbPqWG47BVH0v8eBpjzIH+TIdBB2c6OpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}