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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be57a93e74af09a67f8a9f929dc04906138b0f50d3b5d736c4acffe44d3aa492' 
  AND token = 'lP2KCKyc/TNTXd8dpKCkMWS+/NiqFQsh9aHHXDftCN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}