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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99fb8971cf5ca40bbdaf4e884eb602c114d11083e9c0185c3637c0279a5175fa' 
  AND token = 'qOXwE4faFXwR1tdD8GDkIutbl0d5UiNAhcHJpi7NSEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}