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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ba8d761fbef31773b80f5dd0f6290dbcb4443841975e0be63460893cc3a71a6' 
  AND token = 'pr1m1JTs+rNcHi1w00zBee2KeFIhKZzKCJwX6T40wDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}