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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389655dfcd01692cf0f20baef5edad0daccdf2871422c35fcdf4ffe86093d045' 
  AND token = 'c1Y0Y0t5GokuaQD2e45TJ8m8TAWe7lbX67lPUQoVgvY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}