SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d158305d446e6b9973e4fcfb72bf6d775dc653c11c0c8097a547098a397ac24' 
  AND token = '///FDobEg99D0Q0+dynwQnTTlHJsghzyUwJE1K9bKd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}