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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e929f59a4ed80024506f9ab3f0fdb8818a019c45ba0c937854f7c8a2a3c8df7' 
  AND token = '6Er8nLe5bU/USPEyn5OdYv0WpwrSOs11hqS1G09bgIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}