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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e144a57334d9605c4f1bc8d61cf8bd10445df4288877d6989ab48edff465b83b' 
  AND token = 'HfUd3CdAne/B7xO6KaW9pJ5AHIciBqZ5KmwOqdFT9Zw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}